Healing Beyond Symptom Relief

Most people with treatment-resistant depression, anxiety, or PTSD are good candidates for KAP. However, ketamine is not appropriate for everyone. During your medical consultation, our clinicians will review your health history, current medications, and mental health background to determine if KAP is safe and suitable for you. Certain conditions like uncontrolled high blood pressure, active substance use disorders, or a history of psychosis may affect eligibility.

Ketamine works differently than traditional antidepressants. Rather than targeting serotonin or dopamine, ketamine acts on the glutamate system and promotes neuroplasticity—the brain's ability to form new neural connections. This can help break rigid patterns of thinking and behavior associated with depression, anxiety, and trauma. Research shows that when ketamine is combined with therapy, patients are better able to access and process difficult emotions, leading to more lasting change than ketamine alone. The therapeutic relationship and integration work are what help translate these neurological shifts into real-life improvements.

During a dosing session, you'll take a ketamine lozenge that dissolves under your tongue while your therapist is present with you. The effects typically begin within 10-15 minutes and last 45-60 minutes, with the full session running 1-3 hours including time to settle in and reorient afterward. Most people describe feeling deeply relaxed, with a sense of distance from their usual worries. Some experience vivid imagery, emotional releases, or new perspectives on their life. You remain awake and aware throughout, though your sense of time and space may shift. Your therapist is there to provide support and help you feel safe. Afterward, you may feel tired or reflective—it's recommended to rest for the remainder of the day.

You can get a general sense of whether KAP might be right for you based on your symptoms and health history, but a formal eligibility determination requires a medical consultation with our clinical team. That said, speaking with a therapist first is often helpful—they can answer general questions, explain what treatment involves, and help you decide if it feels like a good fit before you move forward with the medical intake.

No. Therapist sessions—including preparation, dosing, and integration—can be done in person or virtually depending on your therapist's practice. When browsing our therapist directory, you can filter by those who offer remote sessions. Medical consultations with our clinical team are always conducted virtually.